Thinking outside the cell: how cell-free hemoglobin can potentiate acute lung injury.

Abstract

intra-alveolar hemorrhage is a pathological feature of acute lung injury (ALI) that was recognized in the first description of the acute respiratory distress syndrome (ARDS) by Ashbaugh and colleagues in 1967 ([2][1]). Over the past four decades, the presence of red blood cells in the air space has