Thin split thickness skin graft with melanocytes for the treatment of large scar with depigmention

Abstract

Objective To investigate the clinical outcome of autologous thin split thickness skin graft with melanocytes for the treatment of large scar with depigmentation, caused by extensive burn. Methods From August 2016 to June 2018, autologous thin split thickness skin graft with melanocytes was used on 19 patients, who had depigmented extensive burn scar. They include 15 males and 4 females, aged 19-54 years. The operation was performed under general anesthesia or local anesthesia. Local mechanical abrasion was carried out at the depigmented surface of the scar, until the superficial dermis. The thin split thickness skin graft with melanocytes was transplanted to the wound at recipient site, followed by package and fixation. The package was kept for two weeks. Results After a follow-up period of 3-6 months, all the grafts survived well with satisfactory appearance. The defects at donor site healed well too. Conclusions Satisfactory outcome can be achieved with autologous thin split thickness skin graft with melanocytes for the treatment of depigmented scar caused by extensive burn. Key words: Melanocytes; Razor graft; Scar; Depigmentation