Abstract

The University of Torino (UniTO) and the National Institute for Nuclear Physics (INFN-TO) are investigating the use of Ultra Fast Silicon Detectors (UFSD) for beam monitoring in radiobiological experiments with therapeutic proton beams. The single particle identification approach of solid state detectors aims at increasing the sensitivity and reducing the response time of the conventional monitoring devices, based on gas detectors. Two prototype systems are being developed to count the number of beam particles and to measure the beam energy with time-of-flight (ToF) techniques. The clinically driven precision (< 1%) in the number of particles delivered and the uncertainty < 1 mm in the depth of penetration (range) in radiobiological experiments (up to 108 protons/s fluxes) are the goals to be pursued. The future translation into clinics would allow the implementation of faster and more accurate treatment modalities, nowadays prevented by the limits of state-of-the-art beam monitors. The experimental results performed with clinical proton beams at CNAO (Centro Nazionale di Adroterapia Oncologica, Pavia) and CPT (Centro di Protonterapia, Trento) showed a counting inefficiency <2% up to 100 MHz/cm2, and a deviation of few hundreds of keV of measured beam energies with respect to nominal ones. The progresses of the project are reported.

Highlights

  • The sensitivity of ionization chambers (ICs), the state-of-the-art beam monitors in charged particle therapy, limits the minimum number of particles that can be safely delivered to the order of thousands per spot, while their slow collection time precludes the use of ICs on fast beam delivery strategies (1)

  • An energy measurement test was performed at CNAO using Hamamatsu Photonics K.K. (HPK) sensors, segmented in 4 pads, each one characterized by a sensitive area of 3x3 mm[2] and depleted region of 80 μm thickness

  • The silicon pads used at CNAO (80 μm active area thickness) showed a time resolution for single particle crossing of 75 – 115 ps, while the silicon strips used at CPT (50 μm active area thickness) showed a time resolution of 40 – 75 ps

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Summary

Introduction

The sensitivity of ionization chambers (ICs), the state-of-the-art beam monitors in charged particle therapy, limits the minimum number of particles that can be safely delivered to the order of thousands per spot, while their slow collection time (hundreds of microseconds) precludes the use of ICs on fast beam delivery strategies (1). Any innovative treatment modalities, such as the ones using less radiation and being faster, cannot be implemented without developing a monitoring system meeting the clinically driven precision of less than 1% in the number of particles delivered and the uncertainty of less than 1mm in the depth of penetration. The first one aimed at counting the number of beam particles up to a fluence of 100MHz/cm[2] and the second one to measure the beam energy with time-of-flight (ToF) techniques, are being developed exploiting the innovative Ultra Fast Silicon Detector (UFSD) technology.

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