Thin Films: A Promising Approach for Drug Delivery System

Abstract

The prime goal of drug delivery through drug carrier system to the specific target site at the suitable concentration for therapeutic action. Recently thin films are acquiring attention as drug carrier and various scientists are working on the formulation and development of thin films as a novel drug delivery system. Because of its capacity to safely load medications and release them in a regulated manner, thin films have attracted increasing interest in the field of drug delivery, which improves drug efficacy. They are more patient compliance and alternative to oral drug delivery employing self-application, prolonged action and easily terminate if drug toxicity is produced. Oral, buccal, sublingual, ocular, and transdermal routes have all been employed to deliver this delivery mechanism for both systemic and local effects. The development of thin films comprises of various methods with keeping in mind the anatomical and physiological constraints, physicochemical properties and types of drug substance and use of various polymers (matrix, hydrophilic and hydrophobic) as well as the characterisation methods with recent trends.