Abstract
Inflammatory breast carcinoma (IBC) is a rare clinicopathological cancer type with unique clinical features and a poor prognosis. In this disease, there is generally no palpable mass in the breast. IBC can be mistakenly diagnosed as mastitis and patients may receive a delayed diagnosis and treatment, since these two disorders cause similar pathological appearences on the breast. Clinical suspicion of the disease followed by histopathological observation of occluded dermal lympthatics by tumor emboli leads to definitive diagnosis of IBC. Here, we report our experiences in diagnosing IBC using Thick-Needle Aspiration Biopsy (TNAB). Eight patients having clinically suspected IBC, received TNAB. IBC was definitively diagnosed upon observation in histopathological examination of occluded dermal lymphatics by tumor emboli since TNAB allowed adequate tissue sampling. In this study, we showed that IBC can be reliably diagnosed using TNAB.
Highlights
Inflammatory breast carcinoma (IBC) is a rare subtype of breast cancers, with unique clinical and pathological features and poor prognosis
Here, we report our experiences in diagnosing IBC using Thick-Needle Aspiration Biopsy (TNAB)
IBC was definitively diagnosed upon observation in histopathological examination of occluded dermal lymphatics by tumor emboli since TNAB allowed adequate tissue sampling
Summary
Inflammatory breast carcinoma (IBC) is a rare subtype of breast cancers, with unique clinical and pathological features and poor prognosis. Since IBC can be mistakenly diagnosed as mastitis, patients may receive a delayed diagnosis and treatment. IBC has a poor prognosis, beneficial outcomes of treatments (e.g. adjuvant therapy and/ or mastectomy) have been reported in a number of studies in some patients diagnosed IBC2. IBC can be possibly diagnosed clinically and radiologically, such breast diseases as granulomatous mastitis[3], tumorlike lymphocytis mastitis[4], diabetic mastopathy[5] and inflammatory metastatic melanoma[6,7] should be kept in mind in differential diagnosis in as much as they may interfere with IBC. IBC is diagnosed definitively upon observation by histopathological examination of occluded dermal lymphatics by tumor emboli. The aim of our study was to diagnose IBC by a simple, easy-to-apply and minimally invasive method with a low cost
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