Theta activity in semantic priming under visual crowding as revealed by magnetoencephalography

Abstract

Crowding refers to impaired object recognition of peripheral visual targets caused by nearby flankers. It has been shown that the response to a word was faster when it was preceded by a semantically related than unrelated crowded prime, demonstrating that semantic priming survives crowding. This study examines neural correlates of semantic priming under visual crowding using magnetoencephalography with four conditions: prime (isolated, crowded) x prime-target relationship (related, unrelated). Participants judged whether the target was a word or a nonword. We found significant differences in θ activity at the left inferior frontal gyrus (IFG) for both isolated and crowded primes when comparing the unrelated and related conditions, although the activation was delayed with the crowded prime compared to the isolated prime. The locations within the IFG were also different: theta-band activation was at BA 45 in the isolated condition and at BA 47 in the crowded condition. Phase-locking-value analysis revealed that bilateral IFG was more synchronized with unrelated prime-target pairs than related pairs regardless of whether the primes were isolated or crowded, indicating the recruitment of the right hemisphere when the prime-target semantic relationship was remote. Finally, the distinct waveform patterns found in the isolated and crowded conditions from both the source localization and PLV analysis suggest different neural mechanisms for processing semantic information with isolated primes versus crowded primes.