Abstract

Cardiovascular diseases are considered as the leading cause of death and almost 80% of deaths from this disease are developed in poor and less developed countries where early detection facilities are less available, along with overlooking the importance of screening. In other words, real-time monitoring of the physiological signals using flexible and wearable biosensors plays an important role in human life style. Thus, the present study aims to propose two dimensional flexible and wearable gold covered plasmonic samples as a physiological signal recorder, in which chips with nano array of resonant nanowire patterns performing in an integrated platform of plasmonic devices. The produced surface plasmon waves in our main chip were paired with an electric wave from the heart pulse and it use for recording and detecting the heartbeat of a toad with high accuracy. This measurement was performed in normal state and under external laser heating process to check the ability of signal recording and also thermoplasmonic effect onto the toad's heart signal. Our results show that our sensor was enough sensitive for detection while raising the body temperature of the toad and changing its heart rate as flatting T and P waves by thermoplasmonic effect.

Highlights

  • Cardiovascular diseases are considered as the leading cause of death and almost 80% of deaths from this disease are developed in poor and less developed countries where early detection facilities are less available, along with overlooking the importance of screening

  • These nanostructures which can sustain collective electron oscillations at their surface to control electromagnetic field localization have been widely used for fabricating the mentioned flexible sensors based on plasmonic enhanced ­resonators[19,20], Raman ­scattering[20], and ­photovoltaic[20] onto different substrates. In these periodic arrays, metallic nanoparticles are physically separated by a period comparable to the wavelength of the incident light which have the ability to scatter light to produce diffracted waves and a constructive interference of the optical fields from individual scatters can lead to a stronger exciting phenomenon, named as plasmonic surface lattice resonance(SLR)[21] on the effect of shape and size of the nanoparticles and the refractive index of construction materials

  • This phenomenon is currently used in a wide range of applications in science and technology; such as biosensing, photovoltaics, photocatalysis, much less it’s promising relationship with for example, spectroscopic techniques, Solar cells, Magneto-Optics and Liquid ­Crystals[22,23,24,25], random ­lasing[26], optical ­filters[27], and photothermal treatment by thermoplasmonic e­ ffect[28]. This efficient and periodic thermoplasmonic effect in two-dimensional (2D) plasmonic nanostructures can help us design and fabricate the head of remote sensor by the aid of 2D plasmonic structures onto flexible substrates to be used as a physiology signal recorder

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Summary

Introduction

Cardiovascular diseases are considered as the leading cause of death and almost 80% of deaths from this disease are developed in poor and less developed countries where early detection facilities are less available, along with overlooking the importance of screening. These nanostructures which can sustain collective electron oscillations at their surface to control electromagnetic field localization have been widely used for fabricating the mentioned flexible sensors based on plasmonic enhanced ­resonators[19,20], Raman ­scattering[20], and ­photovoltaic[20] onto different substrates In these periodic arrays, metallic nanoparticles are physically separated by a period comparable to the wavelength of the incident light which have the ability to scatter light to produce diffracted waves and a constructive interference of the optical fields from individual scatters can lead to a stronger exciting phenomenon, named as plasmonic surface lattice resonance(SLR)[21] on the effect of shape and size of the nanoparticles and the refractive index of construction materials. Different medical treatments and enhanced body temperature in the vicinity of heart or pulse in some diseases like heart arrhythmia can be controlled by neural stimulation and modulation based on photo

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