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Abstract
Detecting the existence of SARS-CoV-2 in the indoor atmosphere is a practical solution to track the prevalence and prevent the spread of the virus. In this work, a thermophoretic approach is presented to collect the novel coronavirus-laden aerosols from the air and accumulate to high concentrations adequate for the sensitivity of viral RNA detection. Among the factors, the density and particle size have negligible effects on particle trajectory, while the vertical coordinates of particles increase with the rise in heating source temperature. When the heating temperature is higher than , all of the particles exit the channel from one outlet; thus, the collecting and accumulating of virus-laden aerosols can be realized. This study provides a potential approach to accelerate the detection of SARS-CoV-2 and avoid a false negative in the following RNA test.
Highlights
The outbreak of Coronavirus disease 2019 (COVID-19) pandemic has caused a dramatic impact on healthcare services and economies in the affected countries[1,2]
The underlying pathogen has been confirmed to be a novel coronavirus, which was named as severe acute respiratory syndrome coronavirus (SARS-CoV-2) by the International Committee on Taxonomy of Viruses[3]
Numerical simulations were conducted by coupling the transfer equations of heat and mass transfer with particle tracing for fluid flow
Summary
The outbreak of Coronavirus disease 2019 (COVID-19) pandemic has caused a dramatic impact on healthcare services and economies in the affected countries[1,2]. The aerosolized virus particles carried by humans are caused by coughing/sneezing, even normal breathing or speech of an infected person[4]. The disease is asseverated to be transmitted by multiple pathways, including direct (deposited on persons) or indirect (deposited on objects) contact and airborne transmission[5]. Respiratory particles are the media of airborne transmission, which are commonly distinguished to be droplets or aerosols based on their aerodynamic diameter[7]. A study conducted by Papinei et al.[9] showed that 80% to 90% of particles generated by human expiratory activities were aerosols, most of which were generated during coughing and the least was from nasal breathing. Under the condition of long exposure to high concentrations of aerosols, inhaled aerosols containing virus can deposit directly along the human respiratory tract, which causes infection in the alveolar tissues of the lower respiratory tract[12]
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