Abstract
Thermophilic fungi survive at a growth temperature above 45°C. Although widely spread in the terrestrial region, they have remained underexplored, diverging from other thermophiles of eubacteria and archaea. Thermophilic fungi elicited a lot of interest due to their ability to produce thermostable and thermotolerant compounds with practical applications in the field of biotechnology. Studies on growth kinetics, physiology, supplement uptake, and protein breakdown rate in thermophilic fungi have provided important information on these fungi. Thermophilic fungi can degrade biomass such as polysaccharides into monomers. The characteristics of their enzymes show contrasts among species, just as among strains of comparative species. Some extracellular compounds separated from thermophilic fungi are commercially produced, and a couple of others have the potential due to financial advantages.<br>Thermophilic fungal genes encoding lipase, protease, and various other vital enzymes have been cloned and overexpressed in heterologous fungi for understanding the mechanisms of their natural thermostability and catalysis.
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