Abstract
The aim of the study - thermography-based analysis of lower limb vascular response to thermal impact in patients with trophic disorders, diabetes mellitus and peripheral atherosclerosis. Materials and methods. Thermal impact was carried out using the heating pad acting for 20 minutes. Control of temperature of back of the feet was performed by thermal imaging camera with a thermal sensitivity of 0.02°C. The study involved a group of 8 subjects without vascular disorders of the lower limbs (controls), and patient group of 8 subjects with trophic disorders due to the progression of diabetes and atherosclerosis (age of 67±8 years). All patients had type 2 diabetes and peripheral arterial disease with different levels and the degree of the main arterial occlusion. Intensity of trophic disorders changed from apical necrosis and trophic ulcers to gangrene of the foot. We calculated spectral amplitude parameters and temperature dynamics. Fourier transform was used to perform spectral analysis of temperature data. Results. Temperature response of limbs in patients with diabetes compared with healthy subjects was characterized by monotonous temperature variation without distinct oscillations; reduction in amplitude of oscillations within endothelial temperature range; relatively high average temperature difference between the left and right foot. In the group of healthy subjects reaction on thermal impact is not strictly two-stage, usually interpretable by theory as primary and secondary vasodilation. Conclusions. Decrease of temperature amplitude of endothelial range registered during thermal impact can be the sign of endothelial dysfunction in patients with diabetes and peripheral arterial disease. Spectral and temperature characteristics of reaction of limbs on thermal impact can be used to assess trophic disorders and compensation mechanisms of regulation of metabolic processes in the group of patients with diabetes mellitus.
Highlights
Thermal impact was carried out using the heating pad acting for 20 minutes
Control of temperature of back of the feet was performed by thermal imaging camera with a thermal sensitivity of 0,02 °C
The study involved a group of 8 subjects without vascular disorders of the lower limbs, and patient group of 8 subjects with trophic disorders due to the progression of diabetes and atherosclerosis
Summary
А. Реферат Цель исследования — изучение характера температурной реакции нижних конечностей на тепловую пробу при наличии у пациентов трофических расстройств на фоне сахарного диабета и атеросклероза сосудов нижних конечностей. Устанавливаемое в процессе тепловой пробы снижение амплитуды температурных колебаний эндотелиального диапазона может являться признаком эндотелиальной дисфункции у пациентов с сахарным диабетом 2 типа на фоне атеросклероза сосудов нижних конечностей. Спектральные и температурные параметры реакции конечности на тепловую пробу могут быть использованы для оценки степени трофических расстройств и компенсации механизмов регуляции обменных процессов в группе больных сахарным диабетом. При этом Результаты исследования поиск и совершенствование нагрузочных проб, сти- Средние значения температуры левой и правой мулирующих активность периферических сосудов и стоп приведены в таблице 1 для группы здоровых дающих возможность оценить их функциональные испытуемых, в таблице 2 — для группы пациентов
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