Abstract

In this paper, a novel hybrid texture feature set and fractional derivative filter-based breast cancer detection model is introduced. This paper also introduces the application of a histogram of linear bipolar pattern features (HLBP) for breast thermogram classification. Initially, breast tissues are separated by masking operation and filtered by Grmwald–Letnikov fractional derivative-based Sobel mask to enhance the texture and rectify the noise. A novel hybrid feature set using HLBP and other statistical feature sets is derived and reduced by principal component analysis. Radial basis function kernel-based support vector machine is employed for detecting the abnormality in the thermogram. The performance parameters are calculated using five-fold cross-validation scheme using MATLAB 2015a simulation software. The proposed model achieves the classification accuracy, sensitivity, specificity, and area under the curve of 94.44%, 95.55%, 92.22%, 96.11%, respectively. A comparative investigation of different texture features with respect to fractional order to classify the breast malignancy is also presented. The proposed model is also compared with a few existing state-of-art schemes which verifies the efficacy of the model. Fractional order offers extra adaptability in overcoming the limitations of thermal imaging techniques and assists radiologists in prior breast cancer detection. The proposed model is more generalized which can be used with different thermal image acquisition protocols and IoT based applications.

Highlights

  • Breast cancer has become a widely occuring disease among women and the reason of rapidly increasing death rate due to its late diagnosis [1]

  • This paper introduces a histogram of linear bipolar pattern features (HLBP) for breast thermogram classification

  • Evaluation results show that the proposed model with fractional order filtering, specific feature selection technique, classifier, explicit parameters, and the five-fold cross-validation achieves the highest performance with hybrid texture features at fraction order α = 0.2

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Summary

Introduction

Breast cancer has become a widely occuring disease among women and the reason of rapidly increasing death rate due to its late diagnosis [1]. Deoxyribonucleic acid (DNA) in the cells of breast tissues and these cells keep reproducing the same muted cells These abnormal cells cluster together to form a tumor which becomes cancerous when these abnormal cells metastasize to rest of the body parts through the bloodstream or lymphatic system [2]. The Grumwald–Letnikov definition of the fractional differential is a basic extension of the natural derivative to fractional one and is widely being used in image processing applications [29]. It is described for a function f (x) ∈ [a, b] using Eq (1): ∝ 1∞ m∝ DG−Lf (x) =.

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