Thermal necrosis induced by electrocauterization as a local adjuvant therapy in local aggressive bone tumors, what is the safe limit for surgical margins? An experimental study.

Abstract

In the current study, it was aimed to investigate the temperature change in the cavity wall and pathologic necrosis occurred during cauterization, which was applied at different voltages and time intervals. The right tibias of 32 male rabbits were used. Three 2-mm-diameter holes were created on the cortical surface of the tibia using a hand-held drill. Using an electrocautery device, 55mV was applied for 3 and 5s and 65mV was applied for 3 and 5s. Maximum temperatures at 3 and 6mm distance from the application site were measured. Biopsy specimens obtained at 3 and 6mm distance from the application site were evaluated microscopically for bone cell viability and periosteal necrosis. Thirty-two rabbits were divided into four groups. In all groups, periosteal bone cells located at the region, extending from the application site to 3mm distance, died. In this region, application of 55mV for 3s caused peripheral necrosis. There were significant differences between the four groups in terms of maximum temperatures measured at 3mm distance from the application site (p=0.027). On the other hand, no significant differences were noted between the four groups in terms of maximum temperatures measured at 6mm distance from the application site (p>0.05). Cauterization of the cavity wall in the spray mode at 55mV for 3s after tumor resection caused necrosis in the cavity wall, extending from the application site to 3mm distance. Experimental animal study, Level II.