Thermal damage analysis in tissue caused by electromagnetic radiation using space–time collocation method

Abstract

Over the past half-century, the usage of external heat sources in medical applications has increased substantially. Controlling heat damage is essential for ensuring the efficacy of the treatment. Living tissues are highly non-homogeneous; hence, it is important to take into account the effects of local non-equilibrium on their thermal behavior. In the present study, two- and three- space dimensional time-space fractional single-phase-lag (SPL) and dual-phase-lag (DPL) models for bio-heat transfer in tissue are considered to study the thermal damage and temperature in tissue caused by electromagnetic radiation as an external heat source. The considered mathematical models are more general and consider non-Fourier as well as non-local effects. We obtain the numerical solution for the models by combining Gaussian RBFs and shifted Chebyshev polynomials in the space and time directions, respectively. The RBFs depend on Euclidean distance, so they can easily be used in multidimensional space domain, and the use of Chebyshev polynomials gives spectral accuracy in time direction. It is also explored how different parameters, such as blood perfusion rate Wb, phase lags τq, τt, and fractional derivatives α, β, affect the temperature distribution and thermal damage in the tissue.