Abstract
Phytic acid is a natural compound widely used as depigmenting agent in cosmetic emulsions. Few studies are available in the literature covering the stability and the antioxidating property of this substance, used alone or into emulsions. Therefore, the purpose of this work was to investigate the thermal behavior and antioxidant properties of phytic acid alone and into cosmetic emulsions. The thermal behavior of this substance was evaluated by thermogravimetry (TG)/derivative thermogravimetry (DTG) and differential scanning calorimetry (DSC) and the free-radical-scavenging activity by 1,1-diphenyl-2-picrylhydrazyl (DPPH). TG/DTG and DSC curves allowed evaluation of the thermal behavior of phytic acid. These results showed that the substance presented four stages of mass loss. Thermal decomposition of the material initiated at 150 °C. Thermal behavior of the cosmetic emulsions detected that the addition of phytic acid decreased the thermal stability of the system. DPPH free-radical-scavenging activity showed that phytic acid incorporated into emulsion had no antioxidant capacity compared to BHT. In summary, we concluded that the thermoanalytical techniques (TG and DSC) were efficient and reliable in the characterization of phytic acid alone and incorporated into cosmetic emulsions.
Highlights
Phytic acid is a potent inhibitor of iron-catalyzed hydroxyl radical formation as it chelates the free iron and blocks its coordination site [1]
The carbonization process indicates the beginning of the thermal decomposition process, this fact was not observed in the TG/derivative thermogravimetry (DTG) curves
Our results indicated that phytic acid incorporated into emulsions had a higher scavenging efficiency compared to phytic acid in ethnolic solution, while butylated hydroxytoluene (BHT) incorporated into emulsions presented higher antioxidant activity than phytic acid
Summary
Phytic acid (myo-inositol hexaphosphate, IP6) is a potent inhibitor of iron-catalyzed hydroxyl radical formation as it chelates the free iron and blocks its coordination site [1]. Several studies have uncovered its antioxidant activity in meat products, protective effects against oxidative damage in emulsions and, as a result, have led to an enhancement of shelf life for these products [3]. Phytic acid is largely used as a depigmenting agent, acting through the inhibition of tyrosinase For this reason, phytic acid has been widely used in cosmetic emulsions as an antioxidant for skin care products [5].
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
