Abstract
This article is in response to Jugdaohsingh et al.: The silicon supplement ‘Monomethylsilanetriol’ is safe and increases the body pool of silicon in healthy Pre-menopausal women. Nutrition & Metabolism 2013 10:37: http://www.nutritionandmetabolism.com/content/10/1/37 The response from the authors is published as Jugdaohsingh et al.: Response to Prof D. Vanden Berghe letter: ‘There are not enough data to conclude that Monomethylsilanetriol is safe’. Nutrition & Metabolism 2013 10:65: http://www.nutritionandmetabolism.com/content/10/1/65The authors claim that the silicon supplement 'Monomethylsilanetriol’ (MMST) is safe and is converted to orthosilicic acid (OSA) after ingestion. Critical analysis of the study results indicates that the presented data are insufficient to conclude that the use of MMST in food or food supplements is safe. Long term safety studies in humans and toxicological testing in vitro and in animals are an absolute requisite for such a conclusion but these are lacking in the present study and in the literature. Furthermore, none of the presented data show that MMST is actually converted to OSA, as OSA was not analyzed in neither serum or urine of supplemented subjects.
Highlights
Dear Editor, In the recent article by Jugdaohsingh et al (Nutrition & Metabolism 2013, 10:37) the authors claim that the silicon supplement ‘Monomethylsilanetriol’ (MMST) is safe and is converted to orthosilicic acid (OSA) after ingestion
MMST has been used in liquid food supplements in Europe but no formal safety data are available
This is one of the reasons why The European Food Safety Authorithy (EFSA) [1] has given a negative opinion w.r.t. the use of MMST for nutritional purposes to food supplements and why MMST is not included in Annex II of EC Regulation n ° 1170/2009 [2] which lists the vitamins and minerals and their forms that can be added to food and food supplements
Summary
The authors claim that the silicon supplement ‘Monomethylsilanetriol’ (MMST) is safe and is converted to orthosilicic acid (OSA) after ingestion. Dear Editor, In the recent article by Jugdaohsingh et al (Nutrition & Metabolism 2013, 10:37) the authors claim that the silicon supplement ‘Monomethylsilanetriol’ (MMST) is safe and is converted to orthosilicic acid (OSA) after ingestion. MMST has been used in liquid food supplements in Europe but no formal safety data are available.
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