Therapy results of pericallosal aneurysms: A retrospective unicenter study.

Cornelius Deuschl,Isabel Wanke,Karsten Wrede,Marvin Darkwah Oppong,Christoph Mönninghoff,Hanna Styczen,Ramazan Jabbarli,Alexander Radbruch,Michael Forsting,Ulrich Sure,Lisa Markhardt

doi:10.4081/cp.2020.1257

Cornelius Deuschl, Isabel Wanke + Show 9 more

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https://doi.org/10.4081/cp.2020.1257

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Abstract

This retrospective study aims to compare treatment results of ruptured and unruptured pericallosal artery aneurysms (PAAs) regarding patient outcome and aneurysm recurrence after endovascular treatment (EVT) and neurosurgical treatment (NT). A total of 67 patients with PAA were admitted to our hospital, 44 patients with subarachnoidal hemorrhage (SAH) due to a ruptured PAA and 23 patients with unruptured PAA. The radiographic features of PAA were collected from pre-treatment digital subtraction angiography. In addition, demographic, clinical and radiographic parameters of all patients were recorded. Outcome was measured based on the modified Rankin scale (mRS) at 6 months after admission (favorable mRS score, 0-2 vs unfavorable mRS score, 3-6). Overall 46 patients underwent EVT and 21 patients NT. Six months after discharge 24 patients with SAH had a favorable outcome (mRS 0-2) and 16 patients an unfavorable outcome (mRS 3-6). Mortality rate of patients with SAH was 9.1% (4/44). Overall aneurysm recurrence was treated in 13 % of patients in the EVT cohort (6/46), whereas patients treated with NT had no recurrence. All patients with unruptured PAA had a favorable outcome. EVT and NT of PAA show comparable good results, although aneurysm recurrence occurs more often after EVT.

Highlights

unruptured PAA treated at our neurovascular center in a 15 years period
A total of 64 patients with PAA were admitted to our university hospital
imaging data were retrospectively analyzed by use of the clinical information system and picture archiving

Summary

Introduction

Aneurysms of the pericallosal artery (PA) tend to rupture more frequently and Correspondence: Cornelius Deuschl, Institute of Diagnostic and Interventional Radiology and Neuroradiology University Hospital Essen, Germany. Cornelius Deuschl,[1] Marvin Darkwah Oppong,[2] Hanna Styczen,[1] Lisa Markhardt,[1] Karsten Wrede,[2] Ramazan Jabbarli,[2] Ulrich Sure,[2] cause higher morbidity and mortality rates compared to other supratentorially located aneuryms.[1,2,3]. Neurosurgical treatment (NT) and endovascular treatment (EVT) are. Alexander Radbruch,[1] Michael Forsting,[1] Isabel Wanke,[1,3] Christoph Mönninghoff[1,4] the therapeutic options and are both challenging due to the anatomical localization, small vessel size, and limited microsurgical

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