Abstract
Researchers at University of Pavia, Italy review treatment options for electrical status epilepticus in sleep (ESES)/continuous spikes and waves during slow sleep (CSWS) and their comparative value.
Highlights
Researchers at University of Pavia, Italy review treatment options for electrical status epilepticus in sleep (ESES)/continuous spikes and waves during slow sleep (CSWS) and their comparative value
ESES/CSWS is an age-related, self-limiting disorder characterized by epilepsy with various seizure types, neuropsychological regression, and a typical EEG pattern of continuous epileptiform activity for more than 85% of non-rapid eye movement sleep
When the EEG pattern of ESES is refractory to AEDs, more aggressive therapeutic approaches are considered, but evidence of efficacy is dependent on uncontrolled studies and case reports
Summary
Researchers at University of Pavia, Italy review treatment options for electrical status epilepticus in sleep (ESES)/continuous spikes and waves during slow sleep (CSWS) and their comparative value. ESES/CSWS is an age-related, self-limiting disorder characterized by epilepsy with various seizure types, neuropsychological regression, and a typical EEG pattern of continuous epileptiform activity for more than 85% of non-rapid eye movement (non-REM) sleep. ESES/CSWS is rare, accounting for 0.2-0.5% of childhood epilepsies. The goal of treatment is to control clinical seizures and to improve neuropsychological functions and prevent potential cognitive deterioration.
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