Therapy of dysrhythmias in young women with estrogen deficiency, arterial hypertension, and "metabolically healthy" abdominal obesity

Abstract

Objective. To study the frequency and type of dysrhythmias in young women with arterial hypertension (AH), hypoestrogenemia and «metabolically healthy» abdominal obesity (MHAO), as well as the efficacy of antiarrhythmic drug Allaforte in this cohort of patients. Material and methods. The study included 29 patients with AH, hypoestrogenemia and MHAO, who received the antiarrhythmic drug Allaforte in standard therapy. Patients were comparable in age, severity of course and duration of AH, and therapy. At the beginning of the study and after 4 months of therapy with Allaforte the patients underwent 24-hour ECG Holter monitoring. Results and conclusion. When analyzing the nature and structure of dysrhythmias, it was found that supraventricular extrasystoles, including frequent and allorhythmic ones, are quite often registered in women with AH, estradiol deficiency and MHAO. Similar trends can be traced with respect to the frequency of ventricular arrhythmias. The inclusion of Allaforte in the therapy contributes to the decrease in the number of extrasystoles, normalization of heart rhythm and improvement of general well-being of the patients.