Abstract
Thirty-nine cases of hepatocarcinoma in stage IV were divided into 17 of resected (noncurative resection; group 1) and 22 of nonresected cases (group 2), and studied for the correlations between the prognosis and treatments. Group 1 patients underwent tumor reduction surgery, followed by transcatheter arterial embolization (TAE) and hepatic arterial infusion (HAI) as well as perioperative ethanol injection (EI) for the remnant carcinoma. Group 2 patients who didn't undergo tumor reduction received intensive treatment such as TAE, HAI, EI, hyperthermia and irradiation.Results: 1) In cases of Vp0 and 1, the prognosis of group I was better than that of group II (p<0.05). 2) In cases of Vp2 and 3, there was no significant difference in the prognosis between group I and II. 3) In group I, the prognosis of partial hepatectomy (main tumor resection) was better than that of segmental hepatectomy.These results suggest that tumor reduction surgery, which is not over involvement, with TAE, HAI and EI improve the prognosis of hepatocellular carcinoma even in stage IV of Vp0 or 1.
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