Abstract
Objective To investigate the therapeutic value of endoscopic papillectomy (EP) for duodenal papilla lesion. Methods Patients with duodenal papilla lesion treated with EP from June 2007 to December 2015 were enrolled. The clinical characteristics, EP technical features, complications, the treatment, postoperative recurrence were analyzed. Results A total of 43 patients were enrolled. The mean diameter of the lesion was 22.8±1.2 mm. Thirty-two patients (69.8%) received en bloc resection, and 11 (25.6%) received endoscopic piecemeal mucosal resection (EPMR). After the operation, duodenal papilla lesions recurred in 3 patients (7.0%), 5 patients (11.6%) had delayed bleeding, 4 (9.3%) had postoperative pancreatitis, 6 (14.0%) had long-term bile duct stricture. Intraoperative pancreatic stenting (OR=0.000, 95%CI: 0.000-) was the independent protective factor for postoperative pancreatitis. Pancreatic duct dilation (OR=13.500, 95%CI: 1.400-130.191) was the independent risk factor for postoperative bile duct stenosis. Conclusion EP is minimally invasive with rapid recovery and less cost, and could be recommended for duodenal papilla lesions. Key words: Duodenal diseases; Sphincterotomy, endoscopic; Postoperative complications; Risk factors
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