Abstract

The use of ultrasound in medicine is now quite commonplace, especially with the recentintroduction of small, portable and relatively inexpensive, hand-held diagnostic imaging devices.Moreover, ultrasound has expanded beyond the imaging realm, with methods and applicationsextending to novel therapeutic and surgical uses. These applications broadly include: tissueablation, acoustocautery, lipoplasty, site-specific and ultrasound mediated drug activity,extracorporeal lithotripsy, and the enhancement of natural physiological functions such aswound healing and tissue regeneration. A particularly attractive aspect of this technology is thatdiagnostic and therapeutic systems can be combined to produce totally non-invasive, imageguidedtherapy. This general lecture will review a number of these exciting new applications ofultrasound and address some of the basic scientific questions and future challenges in developingthese methods and technologies for general use in our society. We shall particularly emphasizethe use of High Intensity Focused Ultrasound (HIFU) in the treatment of benign and malignanttumors as well as the introduction of acoustic hemostasis, especially in organs which are difficultto treat using conventional medical and surgical techniques.

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