Abstract
Every one who deals extensively with immune serums realizes that their practical use is attended with certain menaces. These involve manifestations of hypersusceptibility in man. Such a condition may arise in persons in whom a definite previous sensitization has been effected and likewise in those for whom no such sensitization is known or can be conclusively proved. Anaphylactic shock occasionally occurs. So-called serum disease is a more widely known phenomenon. It follows not infrequently on subcutaneous, intravenous or intrathecal injections of animal serums employed for therapeutic purposes and may be delayed or accelerated. The most common symptom is a skin eruption, which is usually urticarial but may vary considerably in type. Edema may appear in various parts of the body, notably the face. Multiple joint pains, albuminuria, leukocytosis and general malaise are sometimes encountered. The possibility of these occurrences may indicate why the use of therapeutic serums awakens hesitancy in
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
