Abstract
Curcumin (diferuloylmethane) derived from the rhizome of Curcuma longa L. has been an active ingredient of traditional Chinese medicine and Ayurvedic medicine for thousands of years to treat liver diseases, rheumatoid diseases, diabetes, atherosclerosis, infectious diseases and cancer. Curcumin has multiple essential pharmacological properties namely, antioxidant, anti-inflammatory, antimutagenic, antimicrobial and anticancer activity. Curcumin inhibits oxidative stress, angiogenesis and inflammatory processes and restore body homeostasis. Its effectiveness was also proved for major eye diseases. In this article, the influence of curcumin on various eye diseases such as dry eye disease, conjunctivitis, pterygium, anterior uveitis, glaucoma, cataract, age-related macular degeneration, diabetic retinopathy, corneal neovascularization, corneal wound healing are reported. Data analysis from several clinical and preclinical investigations indicate that curcumin is highly effective as a therapeutic agent in the treatment of various eye disorders.
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