Abstract

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Highlights

  • National guidelines and consensus documents on onychomycosis diagnosis and treatment were last published more than 5 years ago in 2014 (British7) and 2015 (Canadian1)—around the time that both topical efinaconazole and tavaborole were first approved in the US in 2014

  • Since more clinical data, post hoc analyses, meta-analyses, and FDA-approved indications have become available for onychomycosis drugs

  • Careful assessment and testing must be performed when diagnosing onychomycosis; nail dystrophy can be induced by other disorders, and many common conditions that can mimic onychomycosis should be ruled out (Figure 1)

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Summary

Introduction

National guidelines and consensus documents on onychomycosis diagnosis and treatment were last published more than 5 years ago in 2014 (British7) and 2015 (Canadian1)—around the time that both topical efinaconazole and tavaborole were first approved in the US in 2014. To provide recommendations for the diagnosis and therapeutic treatment of toenail onychomycosis following a roundtable discussion with the authors on March 15, 2021 Patients aged ≥65 years,diabetic, peripheral vascular disease, or immunocompromised topical treatmentb

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