Therapeutic physical factors in treatment programs for patients with chronic pancreatitis

Abstract

The purpose of the study is to study the effectiveness and safety of using therapeutic physical factors in rehabilitation treatment of patients with chronic pancreatitis in hospitals. Material and methods. There has been carried out an open randomized controlled trial which included 95 patients with chronic biliary pancreatitis of stage II-III, moderate severity, in the stage of exacerbation, not requiring surgical treatment. Two groups were formed by simple randomization. The patients of the control group (n = 46) had stationary treatment in accordance with Russian clinical guidelines; in the main group (n = 49) the patients were prescribed low-mineralized mineral water in the form of ingestion and electrophoretics according to the mitigated methods in addition to the treatment complex. Results. The inclusion of low-mineralized sulphate-hydrocarbonate calcium-sodium mineral waters in the treatment complex of patients with chronic pancreatitis in hospitals, their ability to enhance pharmacological potential of the used drugs at the stationary stage provided a significant reduction of clinical and ultrasound indicators with 76.56% of the patients at reduction of pain syndrome in 3.56 (p < 0.01) times, diarrhea - 1.94 (p < 0.01), decrease in enzymatic activity - 3.16 (p < 0.01), acute-phase blood values - in 3.14 (p < 0.01), improvement of metabolic status - in 2.29 (p < 0.01) times. This helped to reduce the length of stay in a 24-hour hospital by 2.7 days, reliably significant in comparison with the data in the control group based on the treatment in accordance with Russian clinical recommendations. In addition, a comparable number of adverse drug reactions were detected in both groups (8.13% verses 10.63%), which indicates equal safety of the used medical technologies. Conclusion. Inclusion of therapeutic physical factors in the complex of treatment of patients with chronic pancreatitis in hospitals provides reliably significant increase of therapeutic measures effectiveness.