Therapeutic mammoplasty is associated with fewer long-term side-effects from breast radiotherapy

Abstract

Background: Larger breast size and volume are predictors of clinically significant radiotherapy side-effects (toxicity). Therapeutic mammoplasty (TM) extends the role of breast-conserving surgery (BCS) by combining wide local excision of the cancer with breast reduction and mastopexy techniques. The aim of this study was to determine the effect of TM using level 2 oncoplastic techniques on the incidence of early and long-term radiotherapy toxicity.