Abstract
Fungal infections occurring in immunocompromised patients after immunochemotherapy treatment are often difficult to eradicate and capable of even being fatal. Systemic mycoses affecting severely immunocompromised patients often manifest acutely with rapidly progressive pneumonia, fungemia, or manifestations of extrapulmonary dissemination. Opportunistic fungal infections (mycoses) include several pathogens elements, as candidiasis, aspergillosis, mucormycosis (zygomycosis) and fusariosis. Prompt diagnosis and effective therapy are needed to improve the associated morbidity and mortality, especially in cases with non-canonical fungal localizations and not responsive to the available antifungal drugs.
Highlights
Introduction ly Fungal infections are an emerging problem in immunocompromised patients with n hematological diseases. Fungal organisms o such as Candida glabrata or tropicalis are e becoming increasingly important in these s areas, as they are increasingly able to acquire resistance to the common drugs and u lead to the death of such patients
In this l case report, we describe the excellent ia results obtained with the experimental comc bination of two antifungal agents in the treatment e of an acute myeloid leukemia patient with disseminated Candida infection
This assom ciation is based on recent evidence of synergy of action m against agents such as Aspergillus and o Candida auris
Summary
Introduction lyFungal infections are an emerging problem in immunocompromised patients with n hematological diseases. ‘Policlinico-San Marco’, Catania; 2Division of Hematology, A.O.U. This drug, was taken irregularly and not continuously, cause low compliance of the patient.
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