Abstract
Objective: To study the outcomes after starting therapeutic hypothermia in our unit. Primary Outcomes: Mortality in Neonatal Intensive Care Unit, neurological examination at discharge, seizures, encephalopathy duration, and mortality up to 18 months were the primary outcomes. Secondary Outcomes: Number of anti-epileptic drugs (AED) at discharge, duration of mechanical ventilation, hospital cost, feeding patterns, duration of hospital stay, and neurodevelopmental outcome at 18 months were the secondary outcomes. Setting: The study was conducted at the NICU, Dr. Mehta's Children Hospital, Chennai. Study Period: October 2013 to December 2015. Conclusion: Therapeutic hypothermia resulted in better survival and neurodevelopmental outcomes though there was no significant reduction in MRI and EEG abnormalities.
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