Abstract

This letter describes a study done at Mulago Hospital Kampala Uganda aimed at determining the feasibility of whole-body cooling by use of simple methods in a low-resource setting. The study performed after written informed parental consent randomly assigned standard care plus therapeutic hypothermia or standard care alone on infants within 3 hours of birth. Data suggests that therapeutic hypothermia with whole-body cooling screening informed consent and randomisation are feasible and inexpensive in a special-care baby unit in a low-resource setting. Rigorous randomised trials to determine the safety and efficacy of therapeutic hypothermia in this context are urgently needed so that any benefi ts of this novel therapy can reach areas of the world that might need it most. (excerpt)

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