Therapeutic hypercapnia. Review

Abstract

In recent years, interest in hypercapnia and its practical applications has grown significantly. An analysis of literature data shows a wide range of systemic and local applications. Due to its powerful effect on blood circulation, vascular elasticity, activation of angiogenesis, and inhibition of pro-inflammatory factors, hypercapnia is already used in dermatology, phlebology, and therapy. Wide opportunities open up for practical use in neurology, given the powerful neuroprotective effect of carbon dioxide, which not only increases tolerance to ischemia, preventing the development of diseases but can also become a tool for the treatment of stroke and heart attack. The antitumor effect and the ability to reduce the level of metabolic processes also make hypercapnia an attractive geroprotector that will help in solving the issue of life extension. Keywords: hypercapnia; hypoxia; cancer; diabetes; neuroprotection; longevity; carboxytherapy; ischemia; stroke