Abstract

Healing of the lesion of tropical ulcer can be promoted by the induction of regional sympathetic block over the affected area. The advantages of extradural block are compared with those possessed by three other techniques. In cases of tropical ulcer the abrupt rise of skin temperature of the leg which follows sympathetic block suggests that the released vessels were in a state of vasospasm. It is postulated that sympathetic hyperactivity is responsible for the vasospasm and affects the peculiar and vulnerable arterioles of the ulcer-prone lower leg. Evidence of morbid changes in the autonomic ganglia in vitamin B deficiency states is reviewed. The aetiology of tropical ulcer may be summarized as “ Skin anoxia and infection” ; in difficult cases treatment should be given for both factors.

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