Therapeutic Efficiency of spirulina against Lead Acetate Toxicity on the Fresh Water Fish Labeo rohita

Abstract

The release of heavy metals in to the aquatic environment causes water pollution problems because of their toxicity, persistence and bioaccumulation. Lead has no known role to play in the human body that is physiologically relevant, and its harmful effects are myriad. Lead from the atmosphere and soil ends up in water bodies thus affecting the aquatic organisms. This situation has thus prompted numerous investigators to study on the effects of this heavy metal on the biological functions of aquatic organisms, particularly on the antioxidant enzyme activity in fish. In the present investigation the effect of lead acetate (heavy metal) on antioxidant enzyme activity was evaluated in the fresh water fish Labeo rohita. The experimental fish were treated with sub lethal concentration of lead acetate (0.015 mg/ L) for 120 hrs. Spirulina was used as supplementary feed during the experimental period. We observed various lead induced lipid peroxidation (LPO), antioxidant enzyme (SOD and CAT) changes and Spirulina supplementary feed therapeutic efficiency was observed in the gill and liver tissues of the fish. All the experimental data are statistically significant at p<0.05% level. The present study was under taken the toxic effect of lead acetate on Labeo rohita fish and chelating property of Spirulina.