Abstract

Therapeutic Efficacy and Tolerability of 30% Versus 70% Concentrations of Topical Trichloroacetic Acid in Patients with Xanthelasma Palpebrarum: A Randomized Clinical Trial

Highlights

  • One of the most frustrating problems in IVF today is the low pregnancy rate in women with poor ovarian response (Webb et al, 2016)

  • Mild Ovarian Stimulation Strategy versus conventional ovarian Stimulation approved by the Ethical Committee of the department of Obstetrics & Gynecology, Minia University

  • Our study was carried at Nile Infertility Center during the period between January 2018 and February 2019.The study included a total of 170 infertile women with an indication for ICSI and characterized as poor responders according to the Bologna criteria

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Summary

Introduction

One of the most frustrating problems in IVF today is the low pregnancy rate in women with poor ovarian response (Webb et al, 2016). Poor responders are estimated to comprise approximately 9-24% of IVF/ICSI patients (Papathanasiou et al, 2016). Aim of the Work: The aim of our study is to compare the efficacy of a mild ovarian stimulation strategy versus a conventional ovarian stimulation in women with poor ovarian response undergoing ICSI. One of the most frustrating problems in IVF today is the low pregnancy rate in women with poor ovarian response(1). Poor responders are estimated to comprise approximately 9-24% of IVF/ICSI patients(2). The other part consists of young women who respond unexpectedly poorly, the physiological decline in the ovarian reserve is the principle factor of low pregnancy outcomes in both groups(4). For example a decreased number of FSH receptors available in granulosa cells, or a defective signal transduction after FSH -receptor binding, the presence of a special FSH receptor - binding inhibitor in the follicular fluid, or the presence of autoantibodies against granulosa cells(6)

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