Abstract
Diabetes mellitus refers to a group of metabolic diseases, in which the patient experiences high levels of blood glucose due to an insufficient production of insulin by the pancreas (Type I diabetes) or an inability of his/her body to respond to the insulin produced (Type II diabetes). <em>Catharanthus roseus</em> (<em>C. roseus</em>) is a plant that belongs to the Apocynaceae family, and has long been used as a natural medicine for Type-1 and Type-2 diabetes in the Ayurvedic system of medicine. This systematic review aims to summarize and provide an overview of the results of several studies that have been conducted to evaluate the plant's antidiabetic efficacy.
Highlights
Diabetes mellitus refers to a group of metabolic diseases, in which the patient experiences high levels of blood glucose due to an insufficient production of insulin by the pancreas (Type 1 diabetes) or an inability of his/ her body to respond to the insulin produced (Type II diabetes) [1]
The results showed that low dose combinations of C. roseus ethanolic extract and Ursolic Acid were optimal for treatment of diabetes and showed the greatest control of blood glucose levels
The results showed that the C. roseus extract exhibited antihyperglycemic activity and reversed most blood and tissue changes caused by STZ-induced diabetes in the rats
Summary
Diabetes mellitus refers to a group of metabolic diseases, in which the patient experiences high levels of blood glucose due to an insufficient production of insulin by the pancreas (Type 1 diabetes) or an inability of his/ her body to respond to the insulin produced (Type II diabetes) [1]. Prolonged periods of high blood sugar levels as characterized by diabetes may lead to severe complications when untreated. This disease is a significant determinant of heart attacks, blindness, kidney failure, stroke, and amputations of limbs [1]. Diabetes mellitus refers to a group of metabolic diseases, in which the patient experiences high levels of blood glucose due to an insufficient production of insulin by the pancreas (Type I diabetes) or an inability of his/her body to respond to the insulin produced (Type II diabetes). This systematic review aims to summarize and provide an overview of the results of several studies that have been conducted to evaluate the plant’s antidiabetic efficacy
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
