Abstract

a peer-reviewed, open access online international journal which publishes original research papers. The journal welcomes submission from scholars and experts for possible publication from all over the world. The scope of the journal includes: Pharmaceutical research, chemistry and biochemistry of naturally occurring compounds, biological evaluation of crude extracts, ethnomedicine, traditional and complementary medicine, ethnopharmacology, biomedical research, Biotechnology, Evaluation of natural substances of land and sea and of plants, microbes and animals, pharmacognosy, bioavailability, clinical, pharmacological, toxicological studies and pharmacokinetics of phytochemicals, Isolation and characterization of compounds, structure elucidation, synthesis and experimental biosynthesis of natural Product as well as developments of methods in these areas are welcomed in the journal.

Highlights

  • Infertility is defined as not getting pregnant despite having frequent, unprotected sex for at least a year for most couples

  • Evaluation of pre-treatment group of patients who had serum LH and FSH levels above the normal limit (LH > 9.8 IU/L; FSH > 5 IU/L) and testosterone levels below the limit of normal showed that the levels of these hormones changed statistically (p < 0.01)

  • The results of the evaluation of serum testosterone, LH, and FSH levels showed that Y10 capsules have the effect of stimulating the body to increase the production of serum testosterone and regulate the secretion of LH and FSH, possibly by acting on the hypothalamic-pituitary-testicular axis

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Summary

Introduction

Infertility is defined as not getting pregnant despite having frequent, unprotected sex for at least a year for most couples. Male infertility tends to increase in countries with low socio-demographic indexes.[3] It is currently estimated that around 30 million men are infertile worldwide, with the highest prevalence regions being Africa and Eastern Europe.[4] Male infertility usually appears between the ages of 18–50, with an average age of 36.5 Epididymal obstruction (1%), azoospermia (14%), and abnormalities in sperm production or function (85%) have been implicated in male infertility.6, 7Previous studies showed that men's sperm quality and quantity were trending down significantly.[8,9] The risk factors associated with infertility were found to be testicular damage, history of mumps, hereditary factors, smoking, alcohol, recreational drugs, psychological stress, obesity, advanced paternal age (APA), and other factors.[10] Traditional medicine has a long history of being effectively used in treating male infertility.[11,12,13,14,15] traditional medicine is considered a useful option for treating infertility in men. Previous studies indicate that herbal medicines can modulate the hypothalamic-

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