THERAPEUTIC EFFECTS OF VITAMIN D IN PATIENTS WITH ACTIVE INFLAMMATORY BOWEL DISORDER: EXAMINING THE RELATION BETWEEN VITAMIN D INTAKE AND DISEASE ACTIVITY

Abstract

Background: Inflammatory bowel diseases include Crohns and ulcerative colitis . They have become more common diseases and lifelong problems for individuals, despite the availability of many medication and surgical alternatives. To achieve the optimum benefits, vitamin D is used to lower disease activity. Objective: This study helps us show the impact and therapeutic effect of vitamin D in active Inflammatory bowel disorder . Methodology: PubMed, the Cochrane Library, and ScienceDirect are the databases searched for randomized controlled trials (RCTs) and reviews. After quality appraisal and cross checking the literature, this systematic review is carried out grounded on Preferred Reporting Items for Systematic Review and Meta-Analysis 2020 (PRISMA 2020) guidelines. A total of 11 studies which include nearly 1500 subjects showed that theres an positive association between VIT D and disease severity . Results: The results suggests that vitamin D administration can significantly lower the inflammation in the gut. An inexpensive VIT D reduced inflammation and drastically bettered the patient lives. Conclusion: To completely understand the complex Relationship between Vitamin D and Inflammatory Bowel Disorder, Large population-sizes trials are highly demanded for further identification and understanding the efficacy of vitamin D with conventional therapy.