Abstract

Effect of fenugreek seed extract on carbendazim-inhibited spermatogenesis in albino ratsHawazen A. Lamfon

Highlights

  • Urolithiasis is a global problem and spans all geographic regions of the world

  • We have reported renoprotective effects of trigonelline based standardized fenugreek seeds extract in animal model of diabetic nephropathy with and without renal ischemic reperfusion in rats (Arora et al, 2012)

  • The data of water consumption and urine parameter measurements such as 24-h volume, pH, uric acid and creatinine is presented as Table 1

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Summary

Introduction

Urolithiasis (stones formation in urinary system) is a global problem and spans all geographic regions of the world. A kidney stone (calculus) is a solid concretion or crystal aggregation formed in the kidneys from dietary minerals in the urine. Kidney calculi formation during urolithiasis is a complex process that results from a succession of several physicochemical events, which include supersaturation, nucleation, growth, aggregation, and retention within the kidneys. Management of kidney calculi depends on the size and location of the stones. Most currently used therapies aim at altering the physical and chemical properties of urine to prevent super saturation of urinary components, which results in their precipitation and stone formation (Moe et al, 2011). Stones larger than 5 mm or stones that fail to pass through; are treated by some surgical interventional procedures such as extracorporeal shock wave

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