Therapeutic effect of micro-invasive vitrectomy for diabetic vitreous hemorrhage

Abstract

Objective To evaluate the safety and efficacy of micro-invasive vitrectomy in cases with dense diabetic vitreous hemorrhage.Methods Retrospective,consecutive,interventional cases series of 82 eyes of 68 patients with diabetic vitreous hemorrhage who underwent 3-port pars plana vitrectomy using 23-guage instrumentation and 25-gauge infusion.Follow-up 9 months (mean 6～16months).Main outcome measures were pre-and post-BCVA,intraocular pressure and complications.Results The postoperative visual acuities improved in 75 eyes (91.5％).The mean BCVA improved from LogMAR1.68±0.57 preoperatively to LogMAR 1.17±0.61 at one week after surgery with significant statistical difference (t =5.44,P ＜0.05).At the final follow-up,the mean BCVA was LogMAR0.58±0.45 which also with significant statistical difference (t =12.75,P ＜0.05) compared with pre-BCVA,and the mean BCVA of patients who had been found macular edema during operation was poor than those had not been found patients.No statistical difference was found among the intraocular pressure of operation day,one day and the following two days after operation.The intraocular pressure of final follow-up was a little higher than pre-operation.There were 6 eyes (7.3％) with recurrent vitreous hemorrhage,temporary intraocular hypertension in 14 eyes (17.1％),neovascular glaucoma in 2 eyes (17.1％),rhegmatogenous retinal detachment in 2 eyes (17.1％).Conclusions Micro-invasive vitrectomy is a feasible treatment for cases with dense diabetic vitreous hemorrhage. Key words: Micro-invasive vitrectomy; Diabetic vitreous hemorrhage; Treatment outcome