Therapeutic effect of different surgical treatments on anal fistula in children

Abstract

Objective To explore the efficacy of different surgical treatments for anal fistula in children. Methods A total of 58 children with anal fistula admitted to our hospital from December 2016 to December 2018 were enrolled in the study. They were randomly divided into the control group and the study group, with 29 cases in each group. The control group was treated with inter-sphincteric fistula ligation, and the study group was treated with inter-sphincteric fistula ligation-Plug. The intraoperative index, cure rate, postoperative pain, anal function, serum inflammatory factors levels, and inflammatory factors levels of drain were compared between the two groups. Results Before surgery, there were no statistically significant differences in serum and drain inflammatory factors levels between the two groups (P>0.05); the amount of bleeding, wound area, and pain duration in the study group were significantly lower than those in the control group, the cure rate of the study group was significantly higher than that of the control group (93.10% vs.72.41%); after surgery, pain score, anal function Wexner score, serum IL-4, IL-6, IL-10 levels, drain IL-6, TNF-α levels in the study group were significantly lower than those in the control group (P<0.05). Conclusion Compared with the traditional inter-sphincteric fistula ligation, the inter-sphincteric fistula ligation-Plug procedure can improve the intraoperative index of children with anal fistula, improve the therapeutic effect, relieve postoperative pain, protect the anus function, reduce the inflammatory response in children, which has a positive effect on postoperative recovery, worthy of clinical promotion. Key words: Inter-sphincteric fistula ligation; Inter-sphincteric fistula ligation-Plug; Anal fistula in children