Abstract

Patients suffering from irritable bowel syndrome (IBS) form a part of the most frequent visitors in GP and gastroenterologist. Pathophysiology of irritable bowel syndrome consists of abnormal bowel motility including the pathological gastro-colic reflex with an abnormal character of stool consistency

Highlights

  • Irritable bowel syndrome (IBS) belongs among the most common disorders diagnosed by GPs and gastroenterologists

  • Antidepressant amitriptyline is safe, well tolerated and effective treatment for patients suffering from IBS with diarrhoea

  • Patients suffering from irritable bowel syndrome (IBS) form a part of the most frequent visitors in GP and gastroenterologist

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Summary

Introduction

Patients suffering from irritable bowel syndrome (IBS) form a part of the most frequent visitors in GP and gastroenterologist. Antidepressant amitriptyline is safe, well tolerated and effective treatment for patients suffering from IBS with diarrhoea. It has been shown in adults with IBS to be significantly more effective than placebo in producing global improvement, increasing feelings of well-being and the same good news concern adolescents and children too. Psychiatrists are the first specialists who started to treat IBS-D patients with amitriptyline after their recognition of unwanted side effects of this antidepressant – constipation [3].

Results
Conclusion

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