Abstract
Prompt start of parenteral antimalarial is essential. The antimalarial treatment of severe disease is being transformed by the development and deployment of the watersoluble artemisinin derivative artesunate. Parenteral artesunate is now the treatment of choice in low-transmission areas and in the 2nd and 3rd trimesters of pregnancy, and research is underway into whether it should replace quinine as the treatment of choice in African children. The development of artesunate suppositories may provide the means to treat patients with severe disease in remote rural settings, potentially buying the time needed to reach a health care facility.
Highlights
Infectious diseases of the nervous system: pathogenesis and worldwide impact Roberto Bruzzone, Monique Dubois-Dalcq, Georges E Grau, Diane E Griffin and Krister Kristensson Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here.
The antimalarial treatment of severe disease is being transformed by the development and deployment of the watersoluble artemisinin derivative artesunate
In areas of high transmission, a significant number of patients with severe febrile illness, including coma, in the presence of a peripheral blood slide with asexual forms of P. falciparum have concomitant bacteraemia
Summary
Infectious diseases of the nervous system: pathogenesis and worldwide impact Roberto Bruzzone, Monique Dubois-Dalcq, Georges E Grau, Diane E Griffin and Krister Kristensson Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. . Therapeutic approaches to severe and cerebral malaria and design of trials Address: Mahidol-Oxford Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand Email: Arjen M Dondorp - arjen@tropmedres.ac from Infectious diseases of the nervous system: pathogenesis and worldwide impact Paris, France. Published: 23 September 2008 BMC Proceedings 2008, 2(Suppl 1):S9
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