Abstract
We present a model of DNA electrophoresis in unentangled polymer solutions based on a new separation mechanism in which the DNA drags along polymer molecules it encounters during migration. Taking into account the deformation and the hydrodynamic resistance of the polymers in the flow, the mutual disengagement time of the DNA and the polymer, and the average number of polymers dragged by one DNA, we build a self-consistent theory leading to predictions for the DNA velocity as a function of the experimental conditions. Our results agree with the data of Barron et al. (1994), and important separation regimes are also identified.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.