Abstract
We perform numerical simulations on a model of DNA molecules during gel electrophoresis in which the effect of periodically changing the applied field by 90° is examined. A random gel is used in this simulation. We find a scaling relationship between mobility and the ratio of the chain length to pulse time for 100 and 200 link chains. Also presented are results for the orientation, with respect to the new field direction, of chains being subjected to periodically varying orthogonal fields. We find no overshoot in this orientation. Results supporting the existence of persistence in the orientation of a chain over several field changes is presented for 400 link chains.
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