Abstract

Isoelectric point values have been determined from a theoretical standpoint for α, β, γ and δ human abnormal subunits bearing elimination or addition of 1–2 different aminoacids with acid-base residues. The charge distribution, in relation to pH values, of the four types of subunits are also reported. These values may be of interest both to predict the electrophoretic behaviour and to characterize human abnormal hemoglobins.

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