Abstract

The resistance to antimicrobial agents has an effect in morbidity and transience from treatment failures and improved health awareness expenses. Although crucial the specific public health risk and estimating the increase in expenses is not an easy responsibility, there is modest uncertainty that growing antibiotic resistance is a severe global problem. Suitable antimicrobial drug use has unquestionable advantage, but physicians and the public frequently use these agents inappropriately. Inappropriate use results from physicians providing antimicrobial drugs to indulge viral infections, using. The simple accessibility of antimicrobial drugs leads to their incorporation into herbal or folk remedies that also increase unsuitable use of these agents. In this present investigation the results of in-vitro antibiotic susceptibility testing, guide clinicians in the suitable selection of initial empiric regimens and, drugs used for individual patients in specific situations are explained in detail.

Highlights

  • AMR [Resistance to antimicrobial agents] has resulted in morbidity and transience from treatment failures and improved health awareness expenses

  • The results of in-vitro antibiotic susceptibility testing, guide clinicians in the suitable selection of initial empiric regimens and, drugs used for individual patients in specific situations

  • For enterococci recovered from blood and CSF, the laboratory should consider determining the actual Minimum Inhibitory Concentration (MIC) for penicillin or ampicillin since E. faecium strains with normal lower level resistance should be considered potentially susceptible to synergy with an aminoglycoside whereas strains with higher level resistance may be resistant to such synergy

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Summary

Introduction

AMR [Resistance to antimicrobial agents] has resulted in morbidity and transience from treatment failures and improved health awareness expenses. Suitable antimicrobial drug use has unquestionable advantage, but physicians and the public frequently use these agents inappropriately. Inappropriate use results from physicians providing antimicrobial drugs to indulge viral infections, using insufficient criteria for diagnosis of infections that potentially have a bacterial aetiology, gratuitously prescribing expensive, broad-spectrum agents, and not following recognized recommendations for using chemo prophylaxis. Antibiotic resistance patterns may differ locally and regionally, so observation data needs to be collected from selected sentinel sources. Patterns can change quickly and they need to be monitored closely because of their implications for public health and as an indicator of appropriate or inappropriate antibiotic usage by physicians in that area. The results of in-vitro antibiotic susceptibility testing, guide clinicians in the suitable selection of initial empiric regimens and, drugs used for individual patients in specific situations

Principle
Factors Influencing Antimicrobial Susceptibility Testing
Moisture
Effects of Thymidine or Thymine
Effects of Variation in Divalent Cations
Testing Strains That Fail to Grow Satisfactorily
Disk Diffusion
Dilution
Disc Diffusion for Fastidious Organisms
Antibiotic Susceptibility Testing for Neisseria Gonorrhoeae
Determination of MIC for Fastidious Organisms
Errors in Interpretation and Reporting Results
Quality Control in Antibiotic Susceptibility Testing
Proficiency testing is repeated for each new drug included in the testing
Detection of Oxacillin-Resistant Coagulase-Negative Staphylococcus Sp
Detection of Imipenem or Meropenem Resistance in Gram-Negative Organisms
Detection of Resistant Enterococci
Application of Computers in Antibacterial Susceptibility Testing
Findings
Conclusions
Full Text
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