Theoretical basis of the method for measuring direct muscular excitability (experimental research)

Abstract

During “in vivo experiments” there was compared the amplitude and shape of induced contractions mechanograms (MGS) with changes in muscle contractions impedanceograms (IGS). It was made with the help of an atraumatic needle electrode for direct myostimulation and registration of muscle contraction impedance. So the impedance decrease was registered at threshold (local) and maximum IGS. The absolute amplitude values of MGS and IGS were changed proportionally, however, the configuration of the MGS and IGS were different. In a way the action potential and local muscle contraction were preceded the beginning of the "mechanical" response. According to the results of the study, the IGS parameters are proportional to the number of open ion channels Ca2+ and can be used to assess the degree of muscle tissue damage based on changes in the parameters of direct muscle excitability (PMV).