Abstract

The effects of different tracer gas diffusivities upon pulmonary gas transport and mixing have been examined by means of a physico-mathematical lung model. Specifically, it is demonstrated how the expired alveolar plateau slope of a tracer gas gives an indication of the magnitude of the end expiratory concentration differences existing in the acinus. Further, by modifying the initial analysis slightly (to allow for a finite flux of gas across the alveolar wall) it has been indicated how more marked stratified inhomogeneities are associated with the transport of soluble rather than isoluble tracer gases.

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