Abstract
The degree to which mucus contributes to airway narrowing and increased airway resistance in fatal asthma was examined in this study. Lungs obtained at coroner’s autopsy were fixed at 25 cm H2O. Cases were classified as control (no history of asthma), nonfatal (previous history of asthma with sudden death not due to asthma attack), or fatal (died of asthma attack). On transverse sections of cartilaginous airways the inner wall area (WAi) from lumen to smooth muscle layer, internal perimeter (Pi), and area of mucus glands (Agland) were measured.
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