Abstract
Thematic Minireview Series: Toward a Structural Basis for Understanding Influenza Virus-Host Cell Interactions
Highlights
Substantial knowledge has been gained about how influenza viruses multiply (1)
Structure and function of the cellular Mx protein that is inducible by interferon and possesses antiviral activity against influenza virus (4)
A minireview that appeared in The Journal of Biological Chemistry in 2006 by Pinto and Lamb (5) focused on the M2 protein of influenza virus, a third viral protein component of the virion envelope in addition to the HA and NA spike glycoproteins (Fig. 1)
Summary
Substantial knowledge has been gained about how influenza viruses multiply (1). The schematic and legend in Fig. 1 summarize the main features of the influenza virus multiplication cycle. Structure and function of the cellular Mx protein that is inducible by interferon and possesses antiviral activity against influenza virus (4). At the Medical Research Council National Institute for Medical Research in London, consider the structural basis of the functional activities of influenza virus HA and NA envelope glycoproteins (2).
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