Abstract
The pDP31 rearrangement polymorphism was studied in 353 individuals encompassing the southern African Khoisan, Negroid and Caucasoid populations. The three alleles representing the ancestral (unrearranged) DNA configuration, the duplication, and the triplication were detected in most of the populations studied. The duplication occurred at higher frequencies in Caucasoid groups than in African populations, whilst the triplication was most common in Negroids. Populations of mixed ancestry exhibited allele frequencies closer to Caucasoids than to Negroids, in accordance with their historical origins.
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